Web2 days ago · ClinicalTrials.gov. A study of Dato-DXd versus investigator’s choice chemotherapy in patients with locally recurrent inoperable or metastatic triple-negative … Web· To evaluate immunogenicity of TDXd. Inclusion Criteria. Inclusion Criteria. Sign and date the tissue screening and main ICFs, prior to the start of any study-specific qualification procedures. ... Systemic therapy must consist of at least 6 cycles of chemotherapy with a total duration of at least 16 weeks, including at least 9 weeks of ...
High response rates with T-DXd in early HER2-low breast cancer
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Antibody-Drug Conjugates Find and Kill Cancer Cells
WebThe US FDA approved our combination targeted therapy for the treatment of pediatric patients with low-grade gliomas containing a specific mutation. This is a significant … WebThis has direct therapeutic relevance, especially considering the recent DESTINY-Breast04, in which a new category of breast cancer patients, HER2-low, had PFS and OS meaningfully improved by use of trastuzumab deruxtecan (TDxd) 81, leading to FDA approval for use of TDxd for this indication. Using AI-based methods to quantify and then stratify ... Web22 hours ago · In cell therapy, the first clinical data will be presented for C-CAR031, a novel transforming growth factor-beta (TGFβ) armoured Glypican 3 (GPC3) targeting chimeric antigen receptor T cell (CAR-T) therapy that is being investigated for liver cancer. Early results show it is well tolerated with promising anti-tumour activity seen with ... my wifi driver is missing