Crystallin promoter
WebSome articles on promoter, crystallin promoter: Perlecan - Expression - Signaling Pathways and Their Effect On Expression - Transcriptional Activation The upstream 2.5 … WebSep 1, 2002 · Thus, the chicken betaB1-crystallin promoter directs high level RNA expression to lens fiber cells, which may be especially useful for the expression of ribozyme and anti-sense RNAs in addition to ...
Crystallin promoter
Did you know?
WebThis study concluded that there existed a TGF-β responsive element in the promoter just 285 base pairs upstream of the transcriptional start site ... porcine TGF-β1 under the lens-specific αA-crystallin promoter and then another similar line was created but with the gene driven by the βb-crystallin promoter, corresponding to another lens ... WebSep 1, 2002 · These data suggest that the chicken β B1-crystallin promoter is the promoter of choice to direct the high level ectopic expression of RNAs to lens fiber cells …
WebCrystallins are a diverse group of abundant soluble proteins that are responsible for the refractive properties of the transparent eye lens. We showed previously that Pax-6 can activate the αB-crystallin/small heat shock protein promoter via the lens-specific regulatory regions LSR1 (−147/−118) and LSR2 (−78/−46).
Web76 of this system. Data on crystallin promoter activity would also facilitate the expression 77 of introduced proteins in zebrafish lens and other tissues. 78 79 A comparison of mouse and zebrafish -crystallin promoter activity can also help detail 80 the evolution of tissue specific expression. Past studies have examined the evolution of WebCrystallin promoters of widely different species are dependent on the same suite of transcription factors and function in similar ways in lens-cells of other species both in culture and in transgenic models (for example: [31–33]). This allows comparison of promoters from both chicken and mouse in mouse cells.
WebWe have further compared the γD-crystallin promoter with the γB-crystallin promoter, the promoter with the most extended developmental expression. We show that the γ …
WebFeb 21, 2024 · The predicted promoter probability and location, and the type of the mutation are shown above each sequence (TSS at position 100). b–d, TERT promoter point mutations predicted by the CNN model... how many episodes needed for syndicationWebDec 1, 2012 · The gene promoter contains response elements for some key transcription factors essential for normal lens development. Prominent among these are factors such as Pax6, c-Maf, Sox2, Prox1, and Six3 [93,94]. In many crystallin gene promoters, elements for lens and non-lens expression are combined in the same 5 ′ region. how many episodes of all creatures season 3WebA DCR1/αA-crystallin promoter (including DCR2) coupled with EGFP virtually recapitulated the expression pattern of αA-crystallin in lens epithelium and fibers. In contrast, the DCR3/αA/EGFP reporter was expressed only in 'late' lens fibers. Chromatin immunoprecipitations showed binding of Pax6 to DCR1 and the αA-crystallin promoter … how many episodes of alter egoWebFeb 21, 2024 · The sequence between SacI and AfeI was replaced with a sequence containing CG-depleted chicken lens δ1-crystallin gene (Sasaki) promoter 51, a … high vldl levels meaningWebJan 15, 2000 · Many of the crystallin promoters have been carefully dissected into component cis -acting elements with critical regions and putative transcription factor binding sites identified ( Cvekl and Piatigorsky, 1996; Duncan et al., 1996; Matsuo et al., 1991 ). how many episodes of alf are thereWebNov 3, 2003 · In order to identify PaxB response elements in the J3-crystallin promoter, we generated a series of J3 promoter deletions in the luciferase reporter construct. The shortest promoter fragment, consisting of only 200 bp upstream of the transcriptional start site, was activated by PaxB and not by PaxB(I84R) (data not shown; but cf. Figure 5C ) . high vo2WebThis present study is the first to show that mammalian α-crystallin promoter function can be analyzed in zebrafish embryos by observing green fluorescent protein (GFP) … how many episodes of alvin and the chipmunks