Cpg 7909 patent
WebOct 3, 2005 · CPG 7909 uses short, synthetic DNA-like molecules, known as CpG, to activate an anti-tumor immune system response. Krieg first described CpG in the mid-1990s as a result of pioneering research in ... WebCPG 7909. Results Immunogenicity study in rabbits. Figure 1 contains the anti-human CETP titers developed in the immunized rabbits. Consistent with previously published data, rabbits immunized with the CETi-1 peptide vaccine adsorbed to Alhydrogel, achieved titers that reached a maximum addition of VaxImmune (CPG 7909) to
Cpg 7909 patent
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WebAug 1, 2004 · For example, CpG 7909 (PF-3512676 or ODN2006), a 24-mer-B-Class CpG ODN and known TLR9 agonists, can induce the production of TNF-α and stimulate and … WebJan 7, 2008 · CPG 7909 was licensed by Pfizer Pharmaceuticals Inc. (New York, NY, USA) for clinical investigation as a single agent or in combination with other therapeutic approaches, and is now known as PF ...
WebFeb 14, 2024 · In Phase 1A, seven Amph modified KRAS and NRAS peptides, G12D, G12R, G12V, G12A, G12C, G12S, G13D (Amph-Peptides 7P) will be evaluated in combination with recommended Phase 2 dose of Amph-CpG-7909 (10.0mg). This Amph-CpG-7909 dose will be evaluated with two Amph-Peptides 7P dose levels (1.4mg and 4.9mg) in 6 subjects … WebOct 23, 2012 · Three US patents relating to CpG 7909 and the use of certain oligonucleotides for treating cancer are due to expire in 2014. Coley also has pending US …
WebCpG oligonucleotide 7909 (CpG 7909, PF-03512676), a synthetic 24mer single stranded agonist of TLR9 expressed by B cells and plasmacytoid dendritic cells, is … WebMar 18, 2024 · CPG 7909 is an immunostimulatory synthetic oligodeoxynucleotide that functions as an adjuvant. It is designed to induce an enhanced immune response. Experimental: AV7909 Lot 2 Participants meeting the entry criteria will be randomized 2:2:2:1 to one of four study groups. Groups 1 to 3 will each receive one of the three …
WebCpG TLR9 antagonist technologies. Three US patents relating to CpG 7909 and the use of certain oligonucleotides for treating cancer are due to expire in 2014. Coley also has …
WebI am part of the PowerObjects' National Healthcare, Retail and CPG team for Dynamics 365. I help customer implement Dynamics 365 across various work streams including … kings creek flowers and giftsWebSep 23, 2005 · We evaluated CPG 7909, a synthetic oligodeoxynucleotide containing immunostimulatory CpG motifs, as an adjuvant to Engerix-B. A randomized, double-blind controlled trial was conducted to determine safety and hepatitis B virus (HBV) immunogenicity in adult HIV subjects on effective antiretroviral therapy. kings creek hoa rehoboth beachWebSynthetic oligodeoxynucleotides (ODNs) containing unmethylated CpG motifs trigger cells that express Toll-like receptor 9 (including human plasmacytoid dendritic cells and B … luzern bibliothek uniWebCpG ODN佐剂为一类已知具有佐剂特性的免疫刺激性寡聚核苷酸,能激活B细胞、NK、DC树突状等细胞,诱导释放IL-12、IFN-γ,从而诱导强Th1型应答和细胞免疫。 该种佐剂也是本领域技术人员所熟知的,已经在现有技术,例如国际申请已经在例如WO 96/02555、WO 99/33488中描述过。 目前已有一些商业化的CpG ODN佐剂,例如CpG 7909... luzern bis thalwilWebAug 12, 2002 · CPG 7909 Plus Herceptin® In Patients With Metastatic Breast Cancer The safety and scientific validity of this study is the responsibility of the study sponsor and … luzern blue ballsWebCOATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; … luzern and hotelWeb调节免疫反应的核酸成分专利检索,调节免疫反应的核酸成分属于·碳水化合物糖其衍生物专利检索,找专利汇即可免费查询专利,·碳水化合物糖其衍生物专利汇是一家知识产权数据服务商,提供专利分析,专利查询,专利检索等数据服务功能。 luzern attraction