Can divalproex cause thrombocytopenia

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August undefined, 2024

WebNov 27, 2024 · Rarely, yes: Most people who take Depakote ( valproic acid) have no impact on their blood. Some people, however, can develop low platelets or low neutrophils or both. Of course, those blood problems may also occur to people taking Depakote but be completely unrelated to the drug. A hematologist is the doctor to sort out the question. WebCommon causes of thrombocytopenia. Primary immune thrombocytopenia (ITP) Drug-induced immune thrombocytopenia (DITP) Heparin (NOTE: special case, also can …

Depakote and Thrombocytopenia - a phase IV clinical …

WebDec 30, 2024 · Valproic acid is a highly protein-bound drug. Serum levels of 50-100 mcg/mL are considered therapeutic, with minimal risk of toxicity when maintained within the … WebMethods: Patients with refractory partial epilepsy were enrolled in this double-blind, multicenter, concentration-response trial that evaluated the efficacy and safety of high … inbox hotmail

Depakote: 7 things you should know - Drugs.com

WebApr 19, 2024 · Thrombocytopenia rarely is inherited; or it can be caused by a number of medications or conditions. Whatever the cause, circulating platelets are reduced by one or more of the following processes: … WebMar 1, 2024 · Valproic acid is used to treat certain types of seizures (epilepsy). This medicine is an anticonvulsant that works in the brain tissue to stop seizures. Valproic acid is also used to treat the manic phase of bipolar disorder (manic-depressive illness), and helps prevent migraine headaches. WebApr 2, 2024 · Thrombocytopenia is a condition that develops because your body does not have enough platelets. Platelets are cells that help your blood to clot. Your body may not be making enough platelets, or it may be destroying too many platelets. When platelets become low, your risk for bleeding increases. Severe bleeding may become life-threatening. inbox hotmail email

Thrombocytopenia: Symptoms, Stages & Treatment - Cleveland Clinic

Valproic Acid-Induced Thrombocytopenia-Related …

WebSide Effects. See also Warning section. Diarrhea, dizziness, drowsiness, hair loss, blurred/ double vision, change in menstrual periods, ringing in the ears, shakiness (tremor), … WebFeb 23, 2024 · bleeding problems and low blood platelet levels; high blood ammonia levels; hypothermia ... Depakote or Depakote ER can cause pancreatitis, which can be life … inbox hotmail 2WebFeb 23, 2024 · Yes, it’s possible for Depakote and Depakote ER to cause long-term side effects. Liver damage, including liver failure, has been reported. Pancreatitis (swelling and damage of the pancreas)... inclass zacatecas

"WebNov 10, 2008 · ITP can be idiopathic, or related to viral infections, autoimmune disorders, lymphoproliferative disorders, or drugs [34, 35]. Classical causes of drug-induced thrombocytopenia are the quinine and quinine-like drugs . The thrombocytopenia is typically sudden, severe, and may be accompanied by bleeding. " - Can divalproex cause thrombocytopenia

Can divalproex cause thrombocytopenia

Causes of thrombocytopenia in adults - UpToDate

WebJan 1, 2001 · Particular attention was paid to the dose and serum level of divalproex sodium coinciding with measurement of the hematologic parameters. Psychiatric diagnoses and medications, as well as general medical conditions and use of medications known to cause thrombocytopenia, were noted. WebAug 17, 2024 · Abdominal pain, nausea, vomiting, diarrhea, constipation, dyspepsia, dizziness, drowsiness, headache, fever, weakness, or weight loss. May also cause bleeding gums, bloating or swelling, cough, a tremor, hair loss, ataxia, nystagmus, a skin rash, somnolence, double vision, infection, and thinking difficulties.

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Web• Pregnancy: Depakote can cause congenital malformations including neural tube defects. Pregnancy registry available (5.2, 8.1) • Pediatric: Children under the age of two years … WebTake this medication by mouth as directed by your doctor. You may take it with food if stomach upset occurs. Swallow the tablet whole. Do not crush or chew the tablet, which …

WebMar 11, 2024 · People with thrombocytopenia can have excessive bleeding. This condition can occur in varying degrees. The risk of bleeding increases as the platelet count decreases. Thrombocytopenia can occur alone. Or, it can develop as a complication of another disease, such as cancer or a viral infection.

WebMar 1, 2024 · Thrombocytopenia (low platelet count) or Viral infection (eg, HIV, cytomegalovirus infection)—Use with caution. May make these conditions worse. Liver disease or ... Divalproex sodium may cause serious allergic reactions affecting multiple … Divalproex sodium is used to treat certain types of seizures (epilepsy). This … WebDec 30, 2024 · It's likely that a routine blood test showing a high platelet count will be your first indication that you have thrombocytosis. Besides taking your medical history, examining you physically and running tests, your doctor might ask about factors that could affect your platelets, such as a recent surgery, a blood transfusion or an infection.

WebJun 27, 2024 · Unexplained thrombocytopenia is a common clinical problem, and the possibility of drug-induced thrombocytopenia must be considered, especially in …

WebDec 19, 2024 · The exact mechanism through which valproate can cause thrombocytopenia is unknown; it can be caused by an increased disruption of platelets as well as by the formation of autoantibodies destroying platelets or by decreased production due to a direct toxic effect on bone marrow [ 3 ]. inbox hostel florianopolisWebNov 2, 2024 · Along with its needed effects, divalproex sodium may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need … inclassnowmcd loginWebAug 22, 2013 · The case demonstrates thrombocytopenia induced by treatment with valproic acid in a relatively young patient after only a week of treatment. The risk of thrombocytopenia caused by valproic acid is 5%, and the risk increases with the age of the patient and with the level of valproic acid in the blood. 4-6 In this case, the patient was … inbox hotmail messagesWebDEPAKOTE can cause other serious side effects, including: Bleeding problems: red or purple spots on your skin, bruising, pain and swelling into your joints due to bleeding or bleeding from your mouth or nose. High ammonia levels in your blood: feeling tired, vomiting, changes in mental status. inbox hotmail not openWebValproate can cause major congenital malformations, particularly neural tube defects (e.g., spina bifida). ... may be dose-related. The probability of thrombocytopenia appears to increase significantly at total valproate concentrations of ... Stopping divalproex sodium extended-release tablets suddenly can cause serious problems. Divalproex ... inclass physicsWebMar 1, 2024 · Propofol. Sodium Oxybate. Vorinostat. Warfarin. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. inclass workWebNov 14, 2024 · Depakote (divalproex sodium) has many possible side effects. Some of the most common ones are stomach-related problems, headache, and drowsiness. More serious Depakote side effects include liver damage, birth defects, and pancreatitis. Talk to your healthcare provider about the risks and benefits of Depakote before you start it. inbox idco